Divergent Transcription: A Driving Force for New Gene Origination?

The mammalian genome is extensively transcribed, a large fraction of which is divergent transcription from promoters and enhancers that is tightly coupled with active gene transcription. Here, we propose that divergent transcription may shape the evolution of the genome by new gene origination.

Bibliographic Details
Main Authors: Sharp, Phillip A., Wu, Xuebing, Ph. D. Massachusetts Institute of Technology
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/109543
https://orcid.org/0000-0003-0369-5269
https://orcid.org/0000-0003-1465-1691