Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

It is increasingly appreciated that oncogenic transformation alters cellular metabolism to facilitate cell proliferation, but less is known about the metabolic changes that promote cancer cell aggressiveness. Here, we analyzed metabolic gene expression in cancer cell lines and found that a set of hi...

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Bibliographic Details
Main Authors: Freinkman, Elizaveta, Comb, William C., Cantor, Jason R., Tam, Wai Leong, Thiru, Prathapan, Kanarek, Naama, Bierie, Brian, Shaul, Yoav, Kim, Dohoon, Chen, Walter W., Possemato, Richard, Reinhardt, Ferenc, Weinberg, Robert A, Yaffe, Michael B, Sabatini, David, Pacold, Michael Edward
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/109548
https://orcid.org/0000-0003-3688-2378
https://orcid.org/0000-0002-7043-5013
https://orcid.org/0000-0002-2401-0030
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/109548
https://orcid.org/0000-0003-3688-2378
https://orcid.org/0000-0002-7043-5013
https://orcid.org/0000-0002-2401-0030
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1446-7256

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