A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends

The Astrin/SKAP complex plays important roles in mitotic chromosome alignment and centrosome integrity, but previous work found conflicting results for SKAP function. Here, we demonstrate that SKAP is expressed as two distinct isoforms in mammals: a longer, testis-specific isoform that was used for...

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Bibliographic Details
Main Authors: Nicholls, Peter K., Kern, David Matthew, Page, David C, Cheeseman, Iain M
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Rockefeller University Press 2017
Online Access:http://hdl.handle.net/1721.1/109584
https://orcid.org/0000-0001-8529-9045
https://orcid.org/0000-0001-9920-3411
https://orcid.org/0000-0002-3829-5612