Solid-phase synthesis provides a modular, lysine-based platform for fluorescent discrimination of nitroxyl and biological thiols
We describe a modular, synthetically facile solid-phase approach aimed at separating the fluorescent reporter and binding unit of small-molecule metal-based sensors. The first representatives contain a lysine backbone functionalized with a tetramethylrhodamine fluorophore, and they operate by modula...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry (RSC)
2017
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Online Access: | http://hdl.handle.net/1721.1/109819 https://orcid.org/0000-0002-9269-7815 https://orcid.org/0000-0002-2693-4982 |