The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design

Dense glycosylation on the HIV-1 envelope glycoprotein hampers the induction of broadly neutralizing antibodies against HIV-1. Zhou et al. remove key glycans to unmask sites of vulnerability and enable the induction of neutralizing antibodies.

Bibliographic Details
Main Authors: Karsten, Christina Beatrice, Alter, Galit
Other Authors: Ragon Institute of MGH, MIT and Harvard
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/109827
https://orcid.org/0000-0003-1570-9445