The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design
Dense glycosylation on the HIV-1 envelope glycoprotein hampers the induction of broadly neutralizing antibodies against HIV-1. Zhou et al. remove key glycans to unmask sites of vulnerability and enable the induction of neutralizing antibodies.
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Elsevier
2017
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| Online Access: | http://hdl.handle.net/1721.1/109827 https://orcid.org/0000-0003-1570-9445 |
| _version_ | 1826214019927638016 |
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| author | Karsten, Christina Beatrice Alter, Galit |
| author2 | Ragon Institute of MGH, MIT and Harvard |
| author_facet | Ragon Institute of MGH, MIT and Harvard Karsten, Christina Beatrice Alter, Galit |
| author_sort | Karsten, Christina Beatrice |
| collection | MIT |
| description | Dense glycosylation on the HIV-1 envelope glycoprotein hampers the induction of broadly neutralizing antibodies against HIV-1. Zhou et al. remove key glycans to unmask sites of vulnerability and enable the induction of neutralizing antibodies. |
| first_indexed | 2024-09-23T15:58:31Z |
| format | Article |
| id | mit-1721.1/109827 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:58:31Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/1098272022-09-29T17:25:24Z The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design Karsten, Christina Beatrice Alter, Galit Ragon Institute of MGH, MIT and Harvard Alter, Galit Dense glycosylation on the HIV-1 envelope glycoprotein hampers the induction of broadly neutralizing antibodies against HIV-1. Zhou et al. remove key glycans to unmask sites of vulnerability and enable the induction of neutralizing antibodies. 2017-06-13T18:08:55Z 2017-06-13T18:08:55Z 2017-04 Article http://purl.org/eprint/type/JournalArticle 2211-1247 http://hdl.handle.net/1721.1/109827 Karsten, Christina Beatrice and Alter, Galit. “The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design.” Cell Reports 19, no. 4 (April 2017): 669–670 © 2017 Elsevier B.V. https://orcid.org/0000-0003-1570-9445 en_US http://dx.doi.org/10.1016/j.celrep.2017.04.033 Cell Reports Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier Elsevier |
| spellingShingle | Karsten, Christina Beatrice Alter, Galit The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design |
| title | The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design |
| title_full | The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design |
| title_fullStr | The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design |
| title_full_unstemmed | The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design |
| title_short | The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design |
| title_sort | hiv 1 glycan shield strategically placed kinks in the armor improve antigen design |
| url | http://hdl.handle.net/1721.1/109827 https://orcid.org/0000-0003-1570-9445 |
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