The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design
Dense glycosylation on the HIV-1 envelope glycoprotein hampers the induction of broadly neutralizing antibodies against HIV-1. Zhou et al. remove key glycans to unmask sites of vulnerability and enable the induction of neutralizing antibodies.
Main Authors: | Karsten, Christina Beatrice, Alter, Galit |
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Other Authors: | Ragon Institute of MGH, MIT and Harvard |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
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Online Access: | http://hdl.handle.net/1721.1/109827 https://orcid.org/0000-0003-1570-9445 |
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