Automated deep-phenotyping of the vertebrate brain

Here, we describe an automated platform suitable for large-scale deep-phenotyping of zebrafish mutant lines, which uses optical projection tomography to rapidly image brain-specific gene expression patterns in 3D at cellular resolution. Registration algorithms and correlation analysis are then used...

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Bibliographic Details
Main Authors: Allalou, Amin, Wu, Yuelong, Ghannad Rezaie, Mostafa, Eimon, Peter, Yanik, Mehmet F
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2017
Online Access:http://hdl.handle.net/1721.1/109843
https://orcid.org/0000-0003-4028-8443
https://orcid.org/0000-0003-0075-1237
https://orcid.org/0000-0003-1928-1909
https://orcid.org/0000-0003-0447-517X