Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

The cytosol-facing membranes of cellular organelles contain proteins that enable signal transduction, regulation of morphology and trafficking, protein import and export, and other specialized processes. Discovery of these proteins by traditional biochemical fractionation can be plagued with contami...

Full description

Bibliographic Details
Main Authors: Udeshi, Namrata D, Svinkina, Tanya, Hung, Victoria, Lam, Stephanie Shih-Min, Guzman, Gaelen Donnelly, Mootha, Vamsi, Carr, Steven A, Ting, Alice Y
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2017
Online Access:http://hdl.handle.net/1721.1/109872
https://orcid.org/0000-0003-3972-2820
https://orcid.org/0000-0002-2687-3470
https://orcid.org/0000-0002-7203-4299
https://orcid.org/0000-0002-8277-5226