Patient-specific modeling of individual sickle cell behavior under transient hypoxia
Sickle cell disease (SCD) is a highly complex genetic blood disorder in which red blood cells (RBC) exhibit heterogeneous morphology changes and decreased deformability. We employ a kinetic model for cell morphological sickling that invokes parameters derived from patient-specific data. This model i...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2017
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Online Access: | http://hdl.handle.net/1721.1/109945 https://orcid.org/0000-0002-0301-0891 |