Patient-specific modeling of individual sickle cell behavior under transient hypoxia
Sickle cell disease (SCD) is a highly complex genetic blood disorder in which red blood cells (RBC) exhibit heterogeneous morphology changes and decreased deformability. We employ a kinetic model for cell morphological sickling that invokes parameters derived from patient-specific data. This model i...
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2017
|
| Online Access: | http://hdl.handle.net/1721.1/109945 https://orcid.org/0000-0002-0301-0891 |