Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing

Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising platform for cardiac studies in vitro, and possibly for tissue repair in humans. However, hiPSC-CM cells tend to retain morphology, metabolism, patterns of gene expression, and electrophysiology similar to that of...

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Bibliographic Details
Main Authors: Gaublomme, Jellert, Shekhar, Karthik, Yi, B. Alexander, Kralj, Joel M., Bloxham, William, Cohen, Adam E., Werley, Christopher A., Chien, Miao-Ping, Butty, Vincent L G, Boyer, Laurie Ann, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2017
Online Access:http://hdl.handle.net/1721.1/109971
https://orcid.org/0000-0003-3491-4962
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/109971
https://orcid.org/0000-0003-3491-4962
https://orcid.org/0000-0001-8567-2049

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