Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising platform for cardiac studies in vitro, and possibly for tissue repair in humans. However, hiPSC-CM cells tend to retain morphology, metabolism, patterns of gene expression, and electrophysiology similar to that of...
Main Authors: | Gaublomme, Jellert, Shekhar, Karthik, Yi, B. Alexander, Kralj, Joel M., Bloxham, William, Cohen, Adam E., Werley, Christopher A., Chien, Miao-Ping, Butty, Vincent L G, Boyer, Laurie Ann, Regev, Aviv |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2017
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Online Access: | http://hdl.handle.net/1721.1/109971 https://orcid.org/0000-0003-3491-4962 https://orcid.org/0000-0001-8567-2049 |
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