An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden on human health because of ZIKV’s neurotropic effects in the course of fetal development. Vaccine candidates against ZIKV are coming online, but immunological tools to study anti-ZIKV responses in preclinical...

Full description

Bibliographic Details
Main Authors: Woodham, Andrew W., Chahal, Jasdave, Fang, Taotao, Khan, Omar Fizal, Ling, Jingjing, Anderson, Daniel Griffith, Ploegh, Hidde
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/110062
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0002-0511-4280
https://orcid.org/0000-0001-5629-4798
https://orcid.org/0000-0002-1090-6071