Small genomic insertions form enhancers that misregulate oncogenes

Small genomic insertions form enhancers that misregulate oncogenes

The non-coding regions of tumour cell genomes harbour a considerable fraction of total DNA sequence variation, but the functional contribution of these variants to tumorigenesis is ill-defined. Among these non-coding variants, somatic insertions are among the least well characterized due to challeng...

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Bibliographic Details
Main Authors:	Hnisz, Denes, Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Abraham, Brian Joseph, Weintraub, Abraham Selby, Kwiatkowski, Nick, Li, Charles Han, Lee, Tong Ihn, Young, Richard A.
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	Nature Publishing Group 2017
Online Access:	http://hdl.handle.net/1721.1/110068 https://orcid.org/0000-0003-0998-9882 https://orcid.org/0000-0001-8091-6112 https://orcid.org/0000-0001-8855-8647

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