Isolation of Circulating Plasma Cells in Multiple Myeloma Using CD138 Antibody-Based Capture in a Microfluidic Device

The necessity for bone marrow aspiration and the lack of highly sensitive assays to detect residual disease present challenges for effective management of multiple myeloma (MM), a plasma cell cancer. We show that a microfluidic cell capture based on CD138 antigen, which is highly expressed on plasma...

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Bibliographic Details
Main Authors: Menachery, Anoop, Talluri, Srikanth, Gonzalez, Gabriel, Fulciniti, Mariateresa, Karp, Jeffrey M., Prabhala, Rao H., Qasaimeh, Mohammad Ameen, Wu, Yichao, Bose, Suman, Karnik, Rohit
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/110070
https://orcid.org/0000-0002-5921-3436
https://orcid.org/0000-0003-0588-9286