Predicting the impact of non-coding variants on DNA methylation

DNA methylation plays a crucial role in the establishment of tissue-specific gene expression and the regulation of key biological processes. However, our present inability to predict the effect of genome sequence variation on DNA methylation precludes a comprehensive assessment of the consequences o...

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Bibliographic Details
Main Authors: Zeng, Haoyang, Gifford, David K
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Oxford University Press 2017
Online Access:http://hdl.handle.net/1721.1/110127
https://orcid.org/0000-0003-1057-2865
https://orcid.org/0000-0003-1709-4034