Nucleic acid-mediated intracellular protein delivery by lipid-like nanoparticles

Intracellular protein delivery has potential biotechnological and therapeutic application, but remains technically challenging. In contrast, a plethora of nucleic acid carriers have been developed, with lipid-based nanoparticles (LNPs) among the most clinically advanced reagents for oligonucleotide...

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Bibliographic Details
Main Authors: Chen, Delai, Veiseh, Omid, Pelet, Jeisa, Yin, Hao, Dong, Yizhou, Anderson, Daniel Griffith, Eltoukhy, Ahmed A.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/110153
https://orcid.org/0000-0001-6898-3793
https://orcid.org/0000-0001-5786-0659
https://orcid.org/0000-0001-5629-4798