Direct Observation of Intermediates Involved in the Interruption of the Bischler–Napieralski Reaction

The first mechanistic investigation of electrophilic amide activation of α,α-disubstituted tertiary lactams and the direct observation of key intermediates by in situ FTIR, 1H, 13C, and 19F NMR in our interrupted Bischler–Napieralski-based synthetic strategy to the aspidosperma alkaloids, including...

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Bibliographic Details
Main Authors: White, Kolby L., Mewald, Marius, Movassaghi, Mohammad
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/110277
https://orcid.org/0000-0003-3080-1063