Direct Observation of Intermediates Involved in the Interruption of the Bischler–Napieralski Reaction
The first mechanistic investigation of electrophilic amide activation of α,α-disubstituted tertiary lactams and the direct observation of key intermediates by in situ FTIR, 1H, 13C, and 19F NMR in our interrupted Bischler–Napieralski-based synthetic strategy to the aspidosperma alkaloids, including...
Main Authors: | White, Kolby L., Mewald, Marius, Movassaghi, Mohammad |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2017
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Online Access: | http://hdl.handle.net/1721.1/110277 https://orcid.org/0000-0003-3080-1063 |
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