Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells

Developmental fate decisions are dictated by master transcription factors (TFs) that interact with cis-regulatory elements to direct transcriptional programs. Certain malignant tumors may also depend on cellular hierarchies reminiscent of normal development but superimposed on underlying genetic abe...

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Bibliographic Details
Main Authors: Suvà, Mario L., Rheinbay, Esther, Gillespie, Shawn M., Patel, Anoop P., Wakimoto, Hiroaki, Rabkin, Samuel D., Riggi, Nicolo, Chi, Andrew S., Cahill, Daniel P., Nahed, Brian V., Curry, William T., Martuza, Robert L., Rivera, Miguel N., Rossetti, Nikki, Kasif, Simon, Beik, Samantha, Kadri, Sabah, Tirosh, Itay, Wortman, Ivo, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Louis, David N., Bernstein, Bradley E.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/110338
https://orcid.org/0000-0001-8567-2049