A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response

Fragile X syndrome, a common form of inherited intellectual disability, is caused by loss of the fragile X mental retardation protein FMRP. FMRP is present predominantly in the cytoplasm, where it regulates translation of proteins that are important for synaptic function. We identify FMRP as a chrom...

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Bibliographic Details
Main Authors: Alpatov, Roman, Nakamoto-Kinoshita, Mika, Blanco, Andres, Chen, Shuzhen, Stützer, Alexandra, Armache, Karim J., Simon, Matthew D., Xu, Chao, Ali, Muzaffar, Murn, Jernej, Prisic, Sladjana, Kutateladze, Tatiana G., Vakoc, Christopher R., Min, Jinrong, Kingston, Robert E., Fischle, Wolfgang, Warren, Stephen T., Shi, Yang, Lesch, Bluma, Page, David C
Other Authors: Howard Hughes Medical Institute
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/110339
https://orcid.org/0000-0001-9920-3411