A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

Finding the components of cellular circuits and determining their functions systematically remains a major challenge in mammalian cells. Here, we introduced genome-wide pooled CRISPR-Cas9 libraries into dendritic cells (DCs) to identify genes that control the induction of tumor necrosis factor (Tnf)...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Parnas, Oren, Jovanovic, Marko, Eisenhaure, Thomas M., Herbst, Rebecca H., Ye, Chun Jimmie, Przybylski, Dariusz, Tirosh, Itay, Satija, Rahul, Raychowdhury, Raktima, Mertins, Philipp, Carr, Steven A., Hacohen, Nir, Regev, Aviv, Dixit, Atray C., Platt, Randall Jeffrey, Sanjana, Neville E, Shalem, Ophir, Zhang, Feng
مؤلفون آخرون:	Institute for Medical Engineering and Science
التنسيق:	مقال
اللغة:	en_US
منشور في:	Elsevier 2017
الوصول للمادة أونلاين:	http://hdl.handle.net/1721.1/110389 https://orcid.org/0000-0003-2193-9001 https://orcid.org/0000-0003-2782-2509

الانترنت

http://hdl.handle.net/1721.1/110389
https://orcid.org/0000-0003-2193-9001
https://orcid.org/0000-0003-2782-2509

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

الانترنت

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