Regulation of mTORC1 by amino acids

The mechanistic target of rapamycin complex I (mTORC1) is a central regulator of cellular and organismal growth, and hyperactivation of this pathway is implicated in the pathogenesis of many human diseases including cancer and diabetes. mTORC1 promotes growth in response to the availability of nutri...

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Detalles Bibliográficos
Autores principales: Bar-Peled, Liron, Sabatini, David
Otros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artículo
Lenguaje:en_US
Publicado: Elsevier 2017
Acceso en línea:http://hdl.handle.net/1721.1/110392
https://orcid.org/0000-0002-1446-7256