ENDOR Spectroscopy and DFT Calculations: Evidence for the Hydrogen-Bond Network Within α2 in the PCET of E. coli Ribonucleotide Reductase
Escherichia coli class I ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides and is composed of two subunits: α2 and β2. β2 contains a stable di-iron tyrosyl radical (Y[subscript 122]•) cofactor required to generate a thiyl radical (C[subscript 439]•) in α2 ove...
Main Authors: | , , , , |
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Format: | Article |
Jezik: | en_US |
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American Chemical Society (ACS)
2017
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Online dostop: | http://hdl.handle.net/1721.1/110405 https://orcid.org/0000-0001-8076-4489 |