Necroptosis-Inducing Rhenium(V) Oxo Complexes

Necroptosis-Inducing Rhenium(V) Oxo Complexes

Rhenium(V) oxo complexes of general formula [ReO(OMe)(N^N)Cl₂], where N^N = 4,7-diphenyl-1,10-phenanthroline, 1, or 3,4,7,8-tetramethyl-1,10-phenanthroline, 2, effectively kill cancer cells by triggering necroptosis, a non-apoptotic form of cell death. Both complexes evoke necrosome (RIP1-RIP3)-depe...

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Bibliographic Details
Main Authors: Suntharalingam, Kogularamanan, Awuah, Samuel, Bruno, Peter Michael, Johnstone, Timothy, Wang, Fang, Lin, Wei, Zheng, Yaorong, Page, Julia E., Hemann, Michael, Lippard, Stephen J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/110417
https://orcid.org/0000-0002-6958-3991
https://orcid.org/0000-0003-3383-0118
https://orcid.org/0000-0002-9192-6858
https://orcid.org/0000-0002-2693-4982

Internet

http://hdl.handle.net/1721.1/110417
https://orcid.org/0000-0002-6958-3991
https://orcid.org/0000-0003-3383-0118
https://orcid.org/0000-0002-9192-6858
https://orcid.org/0000-0002-2693-4982

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