Highly Regioselective Indoline Synthesis under Nickel/Photoredox Dual Catalysis

Nickel/photoredox catalysis is used to synthesize indolines in one step from iodoacetanilides and alkenes. Very high regioselectivity for 3-substituted indoline products is obtained for both aliphatic and styrenyl olefins. Mechanistic investigations indicate that oxidation to Ni(III) is necessary to...

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Bibliographic Details
Main Authors: Tasker, Sarah Zinnen, Jamison, Timothy F
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/110421
https://orcid.org/0000-0003-2315-6983
https://orcid.org/0000-0002-8601-7799