Transitions in genetic toggle switches driven by dynamic disorder in rate coefficients
In biochemical systems, intrinsic noise may drive the system switch from one stable state to another. We investigate how kinetic switching between stable states in a bistable network is influenced by dynamic disorder, i.e., fluctuations in the rate coefficients. Using the geometric minimum action me...
Main Authors: | Chen, Hang, Thill, Peter Daniel, Cao, Jianshu |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
American Institute of Physics (AIP)
2017
|
Online Access: | http://hdl.handle.net/1721.1/110439 https://orcid.org/0000-0003-4878-2366 https://orcid.org/0000-0001-6259-8800 https://orcid.org/0000-0001-7616-7809 |
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