Peptide-Based, Two-Fluorophore, Ratiometric Probe for Quantifying Mobile Zinc in Biological Solutions

Peptide-Based, Two-Fluorophore, Ratiometric Probe for Quantifying Mobile Zinc in Biological Solutions

Small-molecule fluorescent sensors are versatile agents for detecting mobile zinc in biology. Capitalizing on the abundance of validated mobile zinc probes, we devised a strategy for repurposing existing intensity-based sensors for quantitative applications. Using solid-phase peptide synthesis, we c...

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Bibliographic Details
Main Authors: Azrad, Maria, Demark-Wahnefried, Wendy, Frederickson, Christopher J., Zhang, Daniel Y., Lippard, Stephen J., Radford, Robert John
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/110458
https://orcid.org/0000-0002-2693-4982

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http://hdl.handle.net/1721.1/110458
https://orcid.org/0000-0002-2693-4982

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