Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing

Small cell lung carcinoma (SCLC) is a highly lethal, smoking-associated cancer with few known targetable genetic alterations. Using genome sequencing, we characterized the somatic evolution of a genetically engineered mouse model (GEMM) of SCLC initiated by loss of Trp53 and Rb1. We identified alter...

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Xehetasun bibliografikoak
Egile Nagusiak:	Taylor-Weiner, Amaro, Stewart, Chip, Carter, Scott L., Cibulskis, Kristian, McKenna, Aaron, Dooley, Alison, Sougnez, Carrie, Park, Jennifer, Farago, Anna F., Dayton, Talya, Shefler, Erica, Gabriel, Stacey, Getz, Gad, McFadden, David Glenn, Papagiannakopoulos, Thales, Bhutkar, Arjun, Vernon, Amanda, Malstrom, Scott E., Heimann, Megan Kristianne, Parker, Jennifer E., Chen, Frances K., Jacks, Tyler E.
Beste egile batzuk:	Koch Institute for Integrative Cancer Research at MIT
Formatua:	Artikulua
Hizkuntza:	en_US
Argitaratua:	Elsevier 2017
Sarrera elektronikoa:	http://hdl.handle.net/1721.1/110469 https://orcid.org/0000-0001-9587-0233 https://orcid.org/0000-0003-4336-2135 https://orcid.org/0000-0001-5785-8911

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