Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene regulation. In particular, Hi-C revealed that chromosomes of animals are organized into topologically associating domains (TADs), evolutionary conserv...

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Dettagli Bibliografici
Autori principali: Ulianov, Sergey V., Khrameeva, Ekaterina E., Gavrilov, Alexey A., Flyamer, Ilya M., Kos, Pavel, Mikhaleva, Elena A., Penin, Aleksey A., Logacheva, Maria D., Chertovich, Alexander, Gelfand, Mikhail S., Shevelyov, Yuri Y., Razin, Sergey V., Imakaev, Maksim Viktorovich
Altri autori: Massachusetts Institute of Technology. Department of Physics
Natura: Articolo
Lingua:en_US
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
Accesso online:http://hdl.handle.net/1721.1/110522
https://orcid.org/0000-0002-5320-2728

Accesso online

http://hdl.handle.net/1721.1/110522
https://orcid.org/0000-0002-5320-2728

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