Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal folding that were subsequently linked to disease and gene regulation. In particular, Hi-C revealed that chromosomes of animals are organized into topologically associating domains (TADs), evolutionary conserv...

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Bibliographic Details
Main Authors: Ulianov, Sergey V., Khrameeva, Ekaterina E., Gavrilov, Alexey A., Flyamer, Ilya M., Kos, Pavel, Mikhaleva, Elena A., Penin, Aleksey A., Logacheva, Maria D., Chertovich, Alexander, Gelfand, Mikhail S., Shevelyov, Yuri Y., Razin, Sergey V., Imakaev, Maksim Viktorovich
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2017
Online Access:http://hdl.handle.net/1721.1/110522
https://orcid.org/0000-0002-5320-2728

Internet

http://hdl.handle.net/1721.1/110522
https://orcid.org/0000-0002-5320-2728

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