Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

Cells, the basic units of biological structure and function, vary broadly in type and state. Single-cell genomics can characterize cell identity and function, but limitations of ease and scale have prevented its broad application. Here we describe Drop-seq, a strategy for quickly profiling thousands...

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Bibliographic Details
Main Authors: Macosko, Evan Z., Satija, Rahul, Nemesh, James, Shekhar, Karthik, Goldman, Melissa, Tirosh, Itay, Bialas, Allison R., Kamitaki, Nolan, Martersteck, Emily M., Trombetta, John J., Weitz, David A., Sanes, Joshua R., McCarroll, Steven A., Shalek, Alexander K, Regev, Aviv, Basu, Anindita, 1978-
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/110604
https://orcid.org/0000-0001-8567-2049