mRNA length-sensing in eukaryotic translation: reconsidering the “closed loop” and its implications for translational control
Most eukaryotic mRNAs are recruited to the ribosome by recognition of a 5ʹ m7GpppN cap. 30 years of genetic and biochemical evidence point to a role for interaction between the 5ʹ cap-interacting factors and the 3ʹ poly(A)-binding protein in bringing the ends of the mRNA into close proximity and pro...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer-Verlag
2017
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| Online Access: | http://hdl.handle.net/1721.1/110612 https://orcid.org/0000-0001-8281-6916 https://orcid.org/0000-0003-2807-9657 |