The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages

Signalling molecules and pathways that mediate crosstalk between various tumour cellular compartments in cancer metastasis remain largely unknown. We report a mechanism of the interaction between perivascular cells and tumour-associated macrophages (TAMs) in promoting metastasis through the IL-33–ST...

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Bibliographic Details
Main Authors: Yang, Yunlong, Andersson, Patrik, Hosaka, Kayoko, Zhang, Yin, Cao, Renhai, Iwamoto, Hideki, Yang, Xiaojuan, Nakamura, Masaki, Wang, Jian, Zhuang, Rujie, Morikawa, Hiromasa, Braun, Harald, Beyaert, Rudi, Samani, Nilesh, Nakae, Susumu, Hams, Emily, Dissing, Steen, Fallon, Padraic G., Cao, Yihai, Xue, Yuan, Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/110671
https://orcid.org/0000-0003-4255-0492