A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models
Summary: Transcription activator-like effector nucleases (TALENs) are a new class of engineered nucleases that are easier to design to cleave at desired sites in a genome than previous types of nucleases. We report here the use of TALENs to rapidly and efficiently generate mutant alleles of 15 gene...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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其他作者: | |
格式: | 文件 |
语言: | en_US |
出版: |
Elsevier B.V.
2017
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在线阅读: | http://hdl.handle.net/1721.1/110833 https://orcid.org/0000-0003-2782-2509 |