A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models

A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models

Summary: Transcription activator-like effector nucleases (TALENs) are a new class of engineered nucleases that are easier to design to cleave at desired sites in a genome than previous types of nucleases. We report here the use of TALENs to rapidly and efficiently generate mutant alleles of 15 gene...

全面介绍

书目详细资料
Main Authors: Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A.K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, Marta, Gupta, Rajat M., Moisan, Annie, Banks, Eric, Friesen, Max, Schinzel, Robert T., Xia, Fang, Tang, Alexander, Xia, Yulei, Figueroa, Emmanuel, Wann, Amy, Ahfeldt, Tim, Daheron, Laurence, Zhang, Feng, Rubin, Lee L., Peng, Lee F., Chung, Raymond T., Musunuru, Kiran, Cowan, Chad A.
其他作者: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
格式: 文件
语言:en_US
出版: Elsevier B.V. 2017
在线阅读:http://hdl.handle.net/1721.1/110833
https://orcid.org/0000-0003-2782-2509

因特网

http://hdl.handle.net/1721.1/110833
https://orcid.org/0000-0003-2782-2509

相似书籍