Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB

Age is well-known to be a significant factor in both disease pathology and response to treatment, yet the molecular changes that occur with age in humans remain ill-defined. Here, using transcriptome profiling of healthy human male skin, we demonstrate that there is a period of significantly elevate...

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Bibliographic Details
Main Authors: Haustead, Daniel J., Stevenson, Andrew, Saxena, Vishal, Marriage, Fiona, Firth, Martin, Silla, Robyn, Martin, Lisa, Adcroft, Katharine F., Rea, Suzanne, Day, Philip J., Melton, Phillip, Wood, Fiona M., Fear, Mark W.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: Springer Nature 2017
Online Access:http://hdl.handle.net/1721.1/110863