Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB
Age is well-known to be a significant factor in both disease pathology and response to treatment, yet the molecular changes that occur with age in humans remain ill-defined. Here, using transcriptome profiling of healthy human male skin, we demonstrate that there is a period of significantly elevate...
Main Authors: | Haustead, Daniel J., Stevenson, Andrew, Saxena, Vishal, Marriage, Fiona, Firth, Martin, Silla, Robyn, Martin, Lisa, Adcroft, Katharine F., Rea, Suzanne, Day, Philip J., Melton, Phillip, Wood, Fiona M., Fear, Mark W. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Springer Nature
2017
|
Online Access: | http://hdl.handle.net/1721.1/110863 |
Similar Items
-
NF-κB Fans the Flames of Lung Carcinogenesis
by: Wong, Kwok-Kin, et al.
Published: (2014) -
The Inflammatory Response to Double Stranded DNA in Endothelial Cells Is Mediated by NFκB and TNFα
by: Patel, Suraj J., et al.
Published: (2011) -
The NF-κB Genomic Landscape in Lymphoblastoid B Cells
by: Zhao, Bo, et al.
Published: (2016) -
The role of ELKS isoforms in leptin and NF-κB signaling.
by: Woo, Yissue.
Published: (2012) -
Transcriptional regulation during aberrant activation of NF-κB signalling in cancer
by: Deka, Kamalakshi, et al.
Published: (2023)