Retro-biosynthetic screening of a modular pathway design achieves selective route for microbial synthesis of 4-methyl-pentanol

Increasingly complex metabolic pathways have been engineered by modifying natural pathways and establishing de novo pathways with enzymes from a variety of organisms. Here we apply retro-biosynthetic screening to a modular pathway design to identify a redox neutral, theoretically high yielding route...

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Bibliographic Details
Main Authors: Sheppard, Micah James, Kunjapur, Aditya Mohan, Wenck, Spencer J., Jones, Kristala L.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/110922
https://orcid.org/0000-0001-6869-9530
https://orcid.org/0000-0003-0437-3157