Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

Investigation of the pharmacokinetics (PK) of a compound is of significant importance during the early stages of drug development, and therefore several in vitro systems are routinely employed for this purpose. However, the need for more physiologically realistic in vitro models has recently fueled...

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Bibliographic Details
Main Authors: Stokes, Cynthia L, Tsamandouras, Nikolaos, Chen, Wen Li, Edington, Collin D, Griffith, Linda G, Cirit, Murat
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Association of Pharmaceutical Scientists 2017
Online Access:http://hdl.handle.net/1721.1/111036
https://orcid.org/0000-0003-1137-0413
https://orcid.org/0000-0002-5248-871X
https://orcid.org/0000-0002-1801-5548