EFFICIENT CONSTRUCTION OF DISORDERED PROTEIN ENSEMBLES IN A BAYESIAN FRAMEWORK WITH OPTIMAL SELECTION OF CONFORMATIONS

Constructing an accurate model for the thermally accessible states of an Intrinsically Disordered Protein (IDP) is a fundamental problem in structural biology. This problem requires one to consider a large number of conformations in order to ensure that the model adequately represents the range of s...

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Bibliographic Details
Main Authors: Fisher, Charles K, Slavin, Orly, Stultz, Collin M
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: World Scientific Publishing 2017
Online Access:http://hdl.handle.net/1721.1/111063
https://orcid.org/0000-0002-3415-242X