Systematic dissection of genomic features determining transcription factor binding and enhancer function
Enhancers regulate gene expression through the binding of sequence-specific transcription factors (TFs) to cognate motifs. Various features influence TF binding and enhancer function—including the chromatin state of the genomic locus, the affinities of the binding site, the activity of the bound TFs...
| Main Authors: | , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences (U.S.)
2017
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| Online Access: | http://hdl.handle.net/1721.1/111218 https://orcid.org/0000-0001-5410-7274 https://orcid.org/0000-0002-5754-1719 |