Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable
Human immunodeficiency virus (HIV) evolves within infected persons to escape being destroyed by the host immune system, thereby preventing effective immune control of infection. Here, we combine methods from evolutionary dynamics and statistical physics to simulate in vivo HIV sequence evolution, pr...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/111592 https://orcid.org/0000-0003-1467-421X https://orcid.org/0000-0003-1268-9602 |