Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable

Human immunodeficiency virus (HIV) evolves within infected persons to escape being destroyed by the host immune system, thereby preventing effective immune control of infection. Here, we combine methods from evolutionary dynamics and statistical physics to simulate in vivo HIV sequence evolution, pr...

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Bibliographic Details
Main Authors: Barton, John P, Butler, Thomas Charles, Walker, Bruce, Chakraborty, Arup K
Other Authors: Institute for Medical Engineering and Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/111592
https://orcid.org/0000-0003-1467-421X
https://orcid.org/0000-0003-1268-9602