β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X
Synaptic protein synthesis is essential for modification of the brain by experience and is aberrant in several genetically defined disorders, notably fragile X (FX), a heritable cause of autism and intellectual disability. Neural activity directs local protein synthesis via activation of metabotropi...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
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Elsevier
2017
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| Online Access: | http://hdl.handle.net/1721.1/111663 https://orcid.org/0000-0001-6673-4988 |