Enforcement of developmental lineage specificity by transcription factor Oct1
Embryonic stem cells co-express Oct4 and Oct1, a related protein with similar DNA-binding specificity. To study the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and inducible-conditional Oct1-deficient ESC lines. ESCs lacking Oct1 show normal appearance, self...
Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Published: |
eLife Sciences Publications, Ltd
2017
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Online Access: | http://hdl.handle.net/1721.1/111796 https://orcid.org/0000-0001-8567-2049 |