Enforcement of developmental lineage specificity by transcription factor Oct1

Enforcement of developmental lineage specificity by transcription factor Oct1

Embryonic stem cells co-express Oct4 and Oct1, a related protein with similar DNA-binding specificity. To study the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and inducible-conditional Oct1-deficient ESC lines. ESCs lacking Oct1 show normal appearance, self...

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Bibliographic Details
Main Authors:	Shen, Zuolian, Kang, Jinsuk, Shakya, Arvind, Tabaka, Marcin, Jarboe, Elke A, Regev, Aviv, Tantin, Dean
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Published:	eLife Sciences Publications, Ltd 2017
Online Access:	http://hdl.handle.net/1721.1/111796 https://orcid.org/0000-0001-8567-2049

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