Evidence of reduced recombination rate in human regulatory domains

Evidence of reduced recombination rate in human regulatory domains

Background Recombination rate is non-uniformly distributed across the human genome. The variation of recombination rate at both fine and large scales cannot be fully explained by DNA sequences alone. Epigenetic factors, particularly DNA methylation, have recently been proposed to in...

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Bibliographic Details
Main Authors: Ernst, Jason, Liu, Yaping, Sarkar, Abhishek Kulshreshtha, Kheradpour, Pouya, Kellis, Manolis
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central 2017
Online Access:http://hdl.handle.net/1721.1/111975
https://orcid.org/0000-0002-4636-9255

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http://hdl.handle.net/1721.1/111975
https://orcid.org/0000-0002-4636-9255

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