G-quadruplex–forming promoter sequences enable transcriptional activation in response to oxidative stress

Oxidative DNA damage is an implacable consequence of aerobic metabolism and often exacerbated in inflammatory processes that use reactive oxygen species (ROS) both as signaling molecules and as chemical warfare against pathogens. An extensive body of work, recently reviewed in ref. 1, has highlighte...

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Bibliographic Details
Main Author: Fedeles, Bogdan I
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/112221
https://orcid.org/0000-0001-5252-826X