Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism

Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism

The postsynaptic scaffolding protein SH3 and multiple ankyrin repeat domains 3 (SHANK3) is critical for the development and function of glutamatergic synapses. Disruption of the SHANK3-encoding gene has been strongly implicated as a monogenic cause of autism, and Shank3 mutant mice show repetitive g...

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Bibliographic Details
Main Authors: Zang, Ying, Lyman, Katherine, Guo, Baolin, Wu, Shengxi, Gerfen, Charles R., Wang, Wenting, Li, Chenchen, Chen, Qian, Van der Goes, Marie-Sophie, Hawrot, James, Yao, Annie, Gao, Xian, Lu, Congyi, Zhang, Qiangge, Wang, Dongqing, Fu, Zhanyan, Feng, Guoping
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: American Society for Clinical Investigation 2017
Online Access:http://hdl.handle.net/1721.1/112252
https://orcid.org/0000-0002-3546-4740
https://orcid.org/0000-0001-5251-6664
https://orcid.org/0000-0003-3327-465X
https://orcid.org/0000-0002-1069-235X
https://orcid.org/0000-0001-9473-2402
https://orcid.org/0000-0002-8021-277X

Internet

http://hdl.handle.net/1721.1/112252
https://orcid.org/0000-0002-3546-4740
https://orcid.org/0000-0001-5251-6664
https://orcid.org/0000-0003-3327-465X
https://orcid.org/0000-0002-1069-235X
https://orcid.org/0000-0001-9473-2402
https://orcid.org/0000-0002-8021-277X

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