Optogenetic Visualization of Presynaptic Tonic Inhibition of Cerebellar Parallel Fibers
Tonic inhibition was imaged in cerebellar granule cells of transgenic mice expressing the optogenetic chloride indicator, Clomeleon. Blockade of GABA A receptors substantially reduced chloride concentration in granule cells due to block of tonic inhibition. This indicates that tonic inhibition is a...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
Society for Neuroscience
2017
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| Online Access: | http://hdl.handle.net/1721.1/112258 |